blood: Leukocytes (White Blood Cells)

Leukocytes (White Blood Cells)

The leukocytes, or white blood cells, defend the body against infecting organisms and foreign agents, both in the tissues and in the bloodstream itself (see immunity). Human blood contains about 5,000 to 10,000 leukocytes per cubic millimeter; the number increases in the presence of infection. An extraordinary and prolonged proliferation of leukocytes is known as leukemia. This overproduction suppresses the production of normal blood cells. Conversely, a sharp decrease in the number of leukocytes (leukopenia) strips the blood of its defense against infection and is an equally serious condition. A dramatic fall in levels of certain white blood cells occurs in persons with AIDS. Leukocytes as well as erythrocytes are formed from stem cells in the bone marrow. They have nuclei and are classified into two groups: granulocytes and agranulocytes.

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