Miriam (mĭrˈēəm) [key], in the Bible. 1 Sister of Moses and Aaron. After the crossing of the Sea of Reeds, she led the women in the song of Miriam. Later she sided with Aaron against Moses and was stricken with leprosy, but was cured when Moses interceded for her. 2 Descendant of Judah. Miriam and Mary are diverse forms of the same original name.