Pope was born in London of Roman Catholic parents and moved to Binfield in 1700. During his later childhood he was afflicted by a tubercular condition known as Pott's disease that ruined his health and produced a pronounced spinal curvature. He never grew taller than 4 ft 6 in. (1.4 m). His religion debarred him from a Protestant education and from the age of 12 he was almost entirely self-taught.
Although he is known for his literary quarrels, Pope never lacked close friends. In his early years he won the attention of William Wycherley and the poet-critic William Walsh, among others. Before he was 17 Pope was admitted to London society and encouraged as a prodigy. The shortest lived of his friendships was with Joseph Addison and his coterie, who eventually insidiously attacked Pope's Tory leanings. His attachment to the Tory party was strengthened by his warm friendship with Swift and his involvement with the Scriblerus Club.