cyclamate (sĪˌkləmātˌ, –mət) [key], any member of a group of salts of cyclamic acid (cyclohexanesulfamic acid). The sodium and calcium salts were commonly used as artificial sweeteners until 1969, when their use was banned by the U.S. Food and Drug Administration after reports that ingestion of large quantities of cyclamates appeared to cause cancer in some animals. There is no evidence that cyclamates are associated with cancer in humans.

The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2012, Columbia University Press. All rights reserved.

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