sarcoma (särkōˈmə) [key], highly malignant tumor arising in connective- and muscle-cell tissue. It is the result of oncogenes (the cancer causing genes of some viruses) and proto-oncogenes (cancer causing genes in human cells). It may affect bone, cartilage, blood vessels, lymph nodes, and skin. See cancer; neoplasm.
The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2012, Columbia University Press. All rights reserved.