The American Revolution was disastrous for the Iroquois. The confederacy, as such, refused to take part in the conflict but allowed each tribe to decide for itself, and all the tribes, except the Oneida, joined the British. Samuel Kirkland, a Protestant missionary, was largely responsible for winning over the Oneida, who rallied to the side of the colonists after remaining neutral for two years.
Cornplanter, Red Jacket, and Joseph Brant (who was educated by Sir William Johnson) led the Iroquois who remained loyal to the British. Brant, the principal leader of the Iroquois troops, participated with the Tory Rangers of Walter Butler in raids in New York and Pennsylvania, particularly the Cherry Valley and Wyoming Valley massacres. The Continental Congress sent out a punitive expedition under John Sullivan, who in 1779 defeated Butler and his Iroquois allies. After the Revolution, Brant, in contrast to the other two chiefs, remained adamant in his hostility toward the United States.