Chickasha (chĭkˈəshā) [key], city (1990 pop. 14,988), seat of Grady co., S central Okla., on the Washita River; inc. 1898. It lies in an agricultural area. Chickasha manufactures furniture, medical equipment and supplies, house trailers, fabricated metal products, and animal feeds. The Oklahoma College of Liberal Arts is in Chickasha.