Manitowoc (mănˌĭtəwŏkˈ) [key], industrial city (1990 pop. 32,520), seat of Manitowoc co., E Wis., a port of entry on Lake Michigan at the mouth of the Manitowoc River; inc. 1870. Its shipbuilding industry dates from 1847; submarines were made there in World War II. Among the city's varied manufactures are electrical and transportation equipment, malt, foods, toys, metal products, and yachts. The North West Company established a trading post on the site in 1795. Manitowoc and its twin city, Two Rivers, were founded in 1836. Silver Lake College of the Holy Family and a maritime museum are located in the city.