Great Grimsby or Grimsby, city (1991 pop. 139,877), North East Lincolnshire, E central England, at the mouth of the Humber River. It is one of the largest fishing ports in the world. Great Grimsby has an extensive commercial trade in fish, coal, grain, and timber as well as an important frozen food industry. Other production includes rayon, titanium oxide, and chemicals. A college of technology is located there.