Stikine (stĭkēnˈ) [key], river, 335 mi (539 km) long, rising in the Stikine Mts., NW British Columbia, Canada. It flows in an arc west and southwest, crossing SE Alaska, to the Pacific Ocean N of Wrangell Island. It is navigable for c.130 mi (210 km) upstream. It has cut deep gorges in the Coast Mts. The Stikine was one of the routes during the Klondike gold rush (1897–98). It is now a chief route to the Cassiar mining region of N British Columbia. The river is a noted salmon stream.