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From our dictionary:

a•nath•e•ma

Pronunciation: (u-nath'u-mu), [key]
n.,
pl. -mas.
1. a person or thing detested or loathed: That subject is anathema to him.
2. a person or thing accursed or consigned to damnation or destruction.
3. a formal ecclesiastical curse involving excommunication.
4. any imprecation of divine punishment.
5. a curse; execration.

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