/ Dictionary / Index C Creutzfeldt-Jakob disease: Meaning and Definition of Find definitions for: Creutz'feldt-Ja'kob disease" Pronunciation: (kroits'felt yä'kôp), [key] — Pathol. Pathol. a rare, usually fatal brain disorder caused by an unidentified pathogen and characterized by progressive dementia, blindness, and involuntary movements. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Creuse crevalle Related Content Daily Word Quiz: nefarious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language