/ Dictionary / Index S Santa Clara: Meaning and Definition of Find definitions for: San•ta Cla•ra Pronunciation: (san'tu klar'u for 1 also Sp. sän'tä klä'rä), [key] a city in central Cuba. 189,092. a city in central California, S of San Francisco. 87,746. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Santa Catarina Santa Claus Related Content Daily Word Quiz: loathe Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language