/ Dictionary / Index S Santiago: Meaning and Definition of Find definitions for: San•ti•a•go Pronunciation: (san"tē-ä'gō Sp. sän"tyä'gô), [key] — n. a city in and the capital of Chile, in the central part. 1,759,087. Also calleda city in NW Spain: pilgrimage center; cathedral. 70,893. a city in SW Panama. 14,595. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: santiago (Thesaurus) Santería Santiago de Cuba Related Content Daily Word Quiz: nefarious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language