Vane, Sir John Robert

Vane, Sir John Robert, 1927–2004, British pharmacologist, Ph.D. Oxford, 1953. With B. I. Samuelsson and Sune K. Bergström , Vane was awarded the 1982 Nobel Prize in Physiology or Medicine. The trio won the prize for their identification and description of various compounds known as prostaglandins , which affect such functions as blood pressure and body temperature. Vane's work helped explain the effects on the body of aspirin , the world's most widely used drug and also contributed to the discovery and development of cox-1 and cox-2 inhibitors (see nonsteroidal anti-inflammatory drug ). He was knighted in 1984.

The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2012, Columbia University Press. All rights reserved.

See more Encyclopedia articles on: Medicine: Biographies

Browse By Subject