What does exasperate mean?

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From our dictionary:

ex•as•per•ate

Pronunciation: (
v.ig-zas'pu-rAt";
adj.ig-zas'pur-it), [key]
v., -at•ed, -at•ing,
adj.

v.t.
1. to irritate or provoke to a high degree; annoy extremely: He was exasperated by the senseless delays.
2. Archaic.to increase the intensity or violence of (disease, pain, feelings, etc.).

adj.
Bot.rough; covered with hard, projecting points, as a leaf.