Quids, in U.S. political history, an extreme states' rights group of Jeffersonian Republicans led by John Randolph of Virginia. Feeling that Thomas Jefferson and James Madison had retreated from the states' rights position they had taken in the Kentucky and Virginia Resolutions and that they had in fact become nationalists, the Quids tried to deprive Madison of the Democratic-Republican presidential nomination in 1808. Their candidate, James Monroe, however, received sizable support only in Virginia, and Jefferson's prestige secured Madison's nomination.
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