Nontropical sprue can be fatal, particularly if growth abnormalities are ignored or unrecognized. It is not known if scrupulous adherence to a gluten-free diet in this disease decreases the likelihood of intestinal lymphoma, but the deletion of gluten from the diet and the intake of vitamin, mineral, and hematinic supplements facilitate remission. Steroid treatments are often used if a gluten-free diet is ineffective if steroid treatment is ineffective the prognosis is not good.
The symptoms of both types of sprue are generally the same: diarrhea with bulky, frothy, foul-smelling stools containing large amounts of fatty acids and soaps, and later weight loss, anemia, and other symptoms related to malabsorption of vitamins. X-ray examination of the small intestine revealing dilation, segmentation, and other typical changes is used in diagnosis.
The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2012, Columbia University Press. All rights reserved.
See more Encyclopedia articles on: Pathology
Browse By Subject
- Earth and the Environment +-
- History +-
- Literature and the Arts +-
- Medicine +-
- People +-
- Philosophy and Religion +-
- Places +-
- Australia and Oceania
- Britain, Ireland, France, and the Low Countries
- Commonwealth of Independent States and the Baltic Nations
- Germany, Scandinavia, and Central Europe
- Latin America and the Caribbean
- Oceans, Continents, and Polar Regions
- Spain, Portugal, Italy, Greece, and the Balkans
- United States, Canada, and Greenland
- Plants and Animals +-
- Science and Technology +-
- Social Sciences and the Law +-
- Sports and Everyday Life +-