Verb

1. anguish, suffer

usage: suffer great pains or distress

2. pain, anguish, hurt, upset, discompose, untune, disconcert, discomfit

usage: cause emotional anguish or make miserable; "It pains me to see my children not being taught well in school"

Adjective

1. anguished, tormented, tortured, sorrowful (vs. joyful)

usage: experiencing intense pain especially mental pain; "an anguished conscience"; "a small tormented schoolboy"; "a tortured witness to another's humiliation"

See also: anguished (Dictionary)