1. fastidious (vs. unfastidious), choosy, choosey, dainty, nice, overnice, prissy, squeamish, finical, finicky, fussy, particular, picky, meticulous, pernickety, persnickety, old-maidish, old-womanish, refined, tidy

usage: giving careful attention to detail; hard to please; excessively concerned with cleanliness; "a fastidious and incisive intellect"; "fastidious about personal cleanliness"

2. fastidious (vs. unfastidious), exacting

usage: having complicated nutritional requirements; especially growing only in special artificial cultures; "fastidious microorganisms"; "certain highly specialized xerophytes are extremely exacting in their requirements"

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See also: fastidious (Dictionary)