/ Thesaurus / H Synonyms of holy of holies Find synonyms for: Noun1. holy of holies, sacrednessusage: (figurative) something regarded as sacred or inviolable; "every politician fears to touch that holy of holies, the Social Security System"2. holy of holies, sanctum sanctorum, sanctuaryusage: (Judaism) sanctuary comprised of the innermost chamber of the Tabernacle in the temple of Solomon where the Ark of the Covenant was keptWordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved. Related Content Daily Word Quiz: cygnet Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language