/ Dictionary / Index I insoluble: Meaning and Definition of Find definitions for: in•sol•u•ble Pronunciation: (in-sol'yu-bul), [key] — adj. incapable of being dissolved: insoluble salts. incapable of being solved or explained: an insoluble problem. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: insoluble (Thesaurus) insolubilize insolvable Related Content Daily Word Quiz: beseech Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language