/ Dictionary / Index Q quadruple run: Meaning and Definition of Find definitions for: quadru'ple run' Pronunciation: [key] — Cribbage. Cribbage. a set of five cards consisting of a three-card run plus two other cards that duplicate different denominations in the run, as 5,5,6,6,7, worth 16 points. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. quadruple quadruplet Related Content Daily Word Quiz: dissonant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language