/ Dictionary / Index S systolic: Meaning and Definition of Find definitions for: sys•tol•ic Pronunciation: (si-stol'ik), [key] — adj. (of blood pressure) indicating the maximum arterial pressure occurring during contraction of the left ventricle of the heart. Cf. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: systolic (Thesaurus) systole systyle Related Content Daily Word Quiz: innocuous Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language