Roxana –sănˈē [key], d. 311 b.c., wife of Alexander the Great. She was the daughter of Oxyartes, a Bactrian baron, and Alexander married her (327) to consolidate his power in Persia. She and Alexander's posthumous son, Alexander IV, were, after Alexander's death, embroiled in the wars of the Diadochi and were imprisoned by Cassander at Amphipolis, Macedon. They were later killed.

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