Borghese bōrgāˈzā [key], Roman noble family, originally of Siena. It produced one pope, Paul V, several cardinals, and many prominent citizens. The Borghese were noted patrons of arts and letters. Scipione Cardinal Borghese built the fine Villa Borghese in Rome. Camillo Borghese, a general under Napoleon I, married his sister Pauline Bonaparte.

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