strychnine strĭk´nĭn [key], bitter alkaloid drug derived from the seeds of a tree, Strychnos nux-vomica, native to Sri Lanka, Australia, and India. It has been used as a rat poison for five centuries, and rat biscuits still remain a cause of accidental poisoning in humans. Strychnine is a potent stimulant of the spinal cord; it also increases the secretion of gastric juices and heightens sensory awareness. Strychnine poisoning is characterized by violent convulsions. It is treated by keeping the victim absolutely quiet and administering barbiturate sedatives and artificial respiration. See first aid.

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