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Santa Fe Railroad

(Encyclopedia)Santa Fe Railroad, former U.S. railroad, chartered in 1863 as the Atchison, Topeka, and Santa Fe RR; opened to traffic in 1864. Construction continued, and in 1880 it reached Santa Fe, N.Mex.; the fol...

Chesapeake and Ohio Canal

(Encyclopedia)Chesapeake and Ohio Canal, former waterway, c.185 mi (300 km) long, from Washington, D.C., to Cumberland, Md., running along the north bank of the Potomac River. A successor to the Potomac Company's (...

cyclic AMP

(Encyclopedia)cyclic AMP: see adenosine monophosphate. ...

Underground Railroad

(Encyclopedia)Underground Railroad, in U.S. history, loosely organized system for helping fugitive slaves escape to Canada or to areas of safety in free states. It was run by local groups of Northern abolitionists,...

Ohio University

(Encyclopedia)Ohio University, main campus at Athens; state supported; coeducational; chartered 1804, opened 1809 as the first college in the Old Northwest. There are additional campuses at Chiillicothe, Lancaster,...

transcontinental railroad

(Encyclopedia)transcontinental railroad, in U.S. history, rail connection with the Pacific coast. In 1845, Asa Whitney presented to Congress a plan for the federal government to subsidize the building of a railroad...

Ohio State University

(Encyclopedia)Ohio State University, main campus at Columbus; land-grant and state supported; coeducational; chartered 1870, opened 1873 as Ohio Agricultural and Mechanical College, renamed 1878. There are also cam...

Erie Railroad

(Encyclopedia)Erie Railroad, rail transportation line designed to connect the mouth of the Hudson River with the Great Lakes region. The New York and Erie RR Company was enfranchised and incorporated in 1832, and c...

Ohio, state, United States

(Encyclopedia)CE5 Ohio, midwestern state in the Great Lakes region of the United States. It is bordered by Pennsylvania (NE), West Virginia (SE) and Kentucky (S) across the Ohio River, Indiana (W), and Michigan ...

Ohio, river, United States

(Encyclopedia)Ohio, river, 981 mi (1,579 km) long, formed by the confluence of the Allegheny and Monongahela rivers in SW Pa., at Pittsburgh; it flows northwest, then generally southwest to enter the Mississippi Ri...