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tamoxifen

(Encyclopedia)tamoxifen təmŏkˈsĭfĕnˌ [key], synthetic hormone used in the treatment of breast cancer. Introduced in 1978, tamoxifen is used to prevent recurrences of cancer in women who have already undergone...

American Academy and Institute of Arts and Letters

(Encyclopedia)American Academy and Institute of Arts and Letters, honorary academy of notable American artists, writers, and composers. The National Institute of Arts and Letters, founded in 1898, served as the par...

fatigue, in physiology

(Encyclopedia)fatigue, in physiology, inability to perform reasonable and necessary physical or mental activity. Muscle fatigue, for example, results when the contractile properties of muscle are reduced, and conti...

Monitor and Merrimack

(Encyclopedia)Monitor and Merrimack, two American warships that fought the first engagement between ironclad ships. When, at the beginning of the Civil War, the Union forces abandoned the Norfolk Navy Yard at Ports...

Bonnie and Clyde

(Encyclopedia)Bonnie and Clyde, Bonnie Parker, 1910–34, b. Rowena, Tex., and Clyde Barrow, 1909–34, b. Tellice, Tex., notorious American criminals during the Great Depression. Joining forces in 1932, they trave...

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