Columbia Encyclopedia

Search results

120 results found

Capecchi, Mario Renato

(Encyclopedia)Capecchi, Mario Renato, 1937–, American geneticist, b. Verona, Italy, Ph.D. Harvard, 1967. On the faculty at Harvard from 1967 to 1973, Capecchi became a professor at the Univ. of Utah School of Med...

mutation

(Encyclopedia)mutation, in biology, a sudden, random change in a gene, or unit of hereditary material, that can alter an inheritable characteristic. Most mutations are not beneficial, since any change in the delica...

Morgan, Thomas Hunt

(Encyclopedia)Morgan, Thomas Hunt, 1866–1945, American zoologist, b. Lexington, Ky., Ph.D. Johns Hopkins, 1890. He was professor of experimental zoology at Columbia (1904–28) and from 1928 was director of the l...

Evans, Sir Martin John

(Encyclopedia)Evans, Sir Martin John, British geneticist, Ph.D., University College London, 1969. After serving on the faculty at University College London (1966–78) and Cambridge (1978–99), he became a profess...

Smithies, Oliver

(Encyclopedia)Smithies, Oliver, 1925–2017, American geneticist, b. Halifax, England, Ph.D., Oxford, 1951. Smithies was on the faculty at the Univ. of Toronto (1953–60) and Univ. of Wisconsin–Madison (1960–8...

antisense

(Encyclopedia)antisense, DNA or RNA manipulated in a laboratory so that its components (nucleotides) form a complementary copy of normal, or “sense,” messenger RNA (mRNA; see nucleic acid). Antisense techniques...

Shimomura, Osamu

(Encyclopedia)Shimomura, Osamu, 1928–2018, Japanese organic chemist and marine biologist, Ph.D. Nagoya Univ., 1960. Shimomura was a researcher at Princeton (1960–82) and a professor (1982–2001) simultaneously...

muscular dystrophy

(Encyclopedia)muscular dystrophy dĭsˈtrōfē [key], any of several inherited diseases characterized by progressive wasting of the skeletal muscles. There are five main forms of the disease. They are classified ac...

Arnold, Frances Hamilton

(Encyclopedia)Arnold, Frances Hamilton, 1956–, American chemical engineer, b. Edgewood, Pa., Ph.D. Univ. of California, Berkeley, 1985. Arnold has been a professor at the California Institute of Technology since ...

cystic fibrosis

(Encyclopedia)cystic fibrosis sĭsˈtĭk fībrōˈsĭs [key], inherited disorder of the exocrine glands (see gland), affecting children and young people; median survival is 25 years in females and 30 years in males...