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Howard Hughes Medical Institute

(Encyclopedia)Howard Hughes Medical Institute, (HHMI), nonprofit medical research organization founded in 1953 by Howard Hughes and largly funded from proceeds of the 1984–85 sale of Hughes Aircraft. Headquartere...

Antiphon, Athenian orator

(Encyclopedia)Antiphon ănˈtĭfŏn, –fən [key], c.479–411 b.c., Athenian orator. He rarely spoke in public but wrote defenses for others to speak. Of his 15 extant orations 3 were for use in court, the rest p...

Pontiac, city, United States

(Encyclopedia)Pontiac, industrial city (1990 pop. 71,166), seat of Oakland co., SE Mich., on the Clinton River; founded 1818 by promoters from Detroit, inc. as a city 1861. Industries developed early and expanded a...

Troyes, Treaty of

(Encyclopedia)Troyes, Treaty of, 1420, agreement between Henry V of England, Charles VI of France, and Philip the Good of Burgundy. Its purpose, ultimately unsuccessful, was to settle the issues of the Hundred Year...

Theramenes

(Encyclopedia)Theramenes thərămˈənēz [key], c.455–404? b.c., Athenian statesman. He helped to establish (411 b.c.) the oligarchical Four Hundred but was later active in overthrowing them. He fought in the Pe...

Rennes

(Encyclopedia)Rennes rĕn [key], city (1990 pop. 203,533), capital of Ille-et-Vilaine dept., NW France, at the junction of the Vilaine and Ille rivers. Rennes's many industrial products include textiles, leather go...

Pylos

(Encyclopedia)Pylos pīˈlŏs [key], ancient harbor, Messenia, SW Greece, on a bay of the Ionian Sea. Excavations have revealed a great Mycenaean palace of the 13th cent. b.c., perhaps the dwelling of King Nestor. ...

Palmer, Alexander Mitchell

(Encyclopedia)Palmer, Alexander Mitchell päˈmər [key], 1872–1936, American politician, b. Moosehead, Pa. Admitted (1893) to the bar, he built up a large law practice, became a leader in the state Democratic pa...

Sluis

(Encyclopedia)Sluis slois [key], municipality, Zeeland prov., SW Netherlands, on the Scheldt estuary, near the Belgian border. Sluis was founded in the 13th cent. and later accorded trading privileges to the Hansea...

Brumaire

(Encyclopedia)Brumaire brümârˈ [key], second month of the French Revolutionary calendar. The coup of 18 (actually 18–19) Brumaire (Nov. 9–10, 1799), engineered chiefly by Sieyès, overthrew the Directory and...