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thalidomide

(Encyclopedia)thalidomide thəlĭdˈəmĭdˌ [key], sleep-inducing drug found to produce skeletal defects in developing fetuses. The drug was marketed in Europe, especially in West Germany and Britain, from 1957 to...

rifampin

(Encyclopedia)rifampin rĭfămˈpĭn [key], antibiotic used in the treatment of tuberculosis. It is also used to eliminate the meningococcus microorganism from carriers and to treat leprosy, or Hansen's disease. Ri...

orphan drug

(Encyclopedia)orphan drug, drug developed under the U.S. Orphan Drug Act (1983) to treat a disease that affects fewer than 200,000 people in the United States. The orphan drug law offers tax breaks and a seven-year...

bugbane

(Encyclopedia)bugbane, any plant of the genus Cimicifuga, tall north-temperate perennials of the family Ranunculaceae (buttercup family). The white spirelike bloom has a rank odor that attracts flies, which pollina...

Webster, John

(Encyclopedia)Webster, John, 1580?–1634, English dramatist, b. London. Although little is known of his life, there is evidence that he worked for Philip Henslowe, collaborating with such playwrights as Dekker and...

Henry I, king of England

(Encyclopedia)Henry I, 1068–1135, king of England (1100–1135), youngest son of William I. He was called Henry Beauclerc because he could write. He quarreled with his elder brothers, William II of England and Ro...

Roger I

(Encyclopedia)Roger I (Roger Guiscard), c.1031–1101, Norman conqueror of Sicily; son of Tancred de Hauteville (see Normans). He went to Italy in 1058 to join his brother, Robert Guiscard, in conquering Apulia and...

Rathlin Island

(Encyclopedia)Rathlin Island răthˈlĭn [key], 5 sq mi (13 sq km), Moyle dist., N Northern Ireland. Its cliffs, of limestone and basalt, rise at Slieveacarn to 449 ft (137 m). Farming and fishing are important. St...

estrogen

(Encyclopedia)CE5 estrogen ĕsˈtrəjən [key], any one of a group of hormones synthesized by the reproductive organs and adrenal glands in females and, in lesser quantities, in males. The estrogens cause the th...

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